We hear a lot about inflammation, and it is sometimes difficult to work out what is enough and when it is too much. The simple answer is to assess your level of pain. If you have pain, you are inflamed.

Inflammation is one of the ways the body minimises injury or infection. As such, it is a vital defence mechanism of the body. The problems begin when acute inflammation becomes chronic, because this can contribute to numerous chronic inflammatory conditions and diseases. Chronic diseases associated with inflammation include Diabetes, Cancer, Bowel disease, Cardiovascular disease and Arthritis.

Inflammation can be caused by infectious factors (pathogens such as viruses or bacteria) or non-infections factors (such as toxins, injury or radiation). Signs of inflammation include swelling, heat, incapacity, pain, redness or loss of function.

It is common practice to suppress the inflammatory response by using drugs such as cortisone. While drugs may work well for acute conditions, and may be lifesaving at times too, it is important to investigate the underlying cause of inflammation in order to eradicate it and the chronic diseases it gives rise to.

A Significant, Unseen Cause of Inflammation: Toxins

Extensive toxicology research has led me to look for the smoking gun, when investigating cause of disease in clients (see an attached example lab report). Time and again, I see evidence of toxins lodged on genes (by means of strong co-valent bonds), as well as on the inner and outer mitochondrial membranes. This is alarmingly important, because genes and cell organelles like the mitochondria are not supposed to have anything piggy-backing them, let alone a toxin!

Toxic Genes

If a gene has a toxin passenger, such as mercury, lead or nickel for example (typical dental amalgam toxins), its core function as a specific protein-making gene is compromised. Simply put, that means that whatever that gene is supposed to be doing, it is not doing to its full capacity. The gene is dysfunctional.

The consequence of a dysfunctional gene is dysfunction or malfunction in the organ or system of the body it is responsible for. This is essentially a coding mistake. When a person is born with a damaged gene it is referred to as a mutation. When this damage happens after birth, it is called an epigenetic factor. Fortunately, it is possible to remove those toxins that are free-loading on our genes!

Toxic Mitochondria

As the all-important fuel cells of the body, the mitochondria are vitally important in maintaining our bodies. If mitochondrial function is compromised, the vital cellular energy is compromised. It has been said that all disease originates as a mitochondrial problem. This makes sense when we note that if we have sufficient energy in our cells to keep all cellular functions running smoothly, we have healthy cells and thus healthy organs. When that cellular energy is compromised, by toxins or disease, it means the organs will be compromised. The organ that shows up as being under the most stress (and sick or dysfunctioning) will be linked to your family genetic weaknesses (cardiovascular, neurodegenerative, diabetic etc, for example).

Where do Toxins come From?

Everywhere, literally (see the list below).

I Eat Well and Have a Clean Lifestyle so Would I be Toxic?

Adding to the unavoidable fact that we are all exposed to environmental toxins daily, is the fact that we all have varying genetic abilities to detoxify our cells (methylation) and flush those toxins out through our liver (phase 1 and phase 2 liver detoxification). These functions of our detoxification systems are what place us in the position to be able to naturally remove toxins from our bodies, if we are eating well and following a clean and healthy lifestyle. Each person is different, and each exposure profile is unique to each person too. That is why some people can smoke heavily and live to a ripe old age, whereas others develop cancer or lung disease. Detoxification ability is genetically geared, and is triggered by toxin exposure. The type of toxin, as well as the amount is important, but the effects differ person to person.

What Can I Do to Reduce Inflammation?

There are a few simple rules of thumb to follow:

Case Study: Woman, 57

Exposure Event: An old metal crown was drilled without use of a rubber dam or strong suction, leading to a large quantity of fine metal being ingested.

Blood Tests: DNA Adducts (see below), Mitochondrial Studies and Hormones.

Symptoms: Within 24 hours a racing heart, anxiety, sore stomach and joint pain. Developed overall body pain, and more joint pain over the coming weeks. Pain is noticeably exacerbated by sugar and gluten (glycation issues, linked to metabolism and the mitochondria).

Supplements: Increased methylation supplements (with folate), and phase 2 liver detoxification supplements (Glutathione and MSM), take an antioxidant complex (with Curcumin) and glucuronidation support supplement (calcium-d-glucarate) to flush xenoestrogens (from dental cement), as the estrogen level had skyrocketed (blood test).

Lab Test Results: DNA ADDUCTS (toxins covalently bonded to genes)

Note: toxins found on the mitochondrial membranes are typically the same as those found on the genes.

b inflammation2

Comment:

Likely Sources of Toxins:

Suggested Additional Support: (hyperlink each one)

Results – Patient Reports:

Research article

Inflammatory responses and inflammation-associated diseases in organs https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5805548/